Ipamorelin is a selective growth hormone releasing peptide (GHRP) that stimulates the pituitary gland to increase growth hormone (GH) secretion without significantly affecting cortisol or prolactin levels. Its high specificity and minimal side effects have made it a valuable peptide in research related to muscle growth, metabolism, and anti-aging therapies (Tripp et al., 2011 [1]).
Ipamorelin acts by binding to the ghrelin receptor (GHS-R1a), mimicking the natural hormone ghrelin. This activation triggers the release of growth hormone in a pulsatile manner, promoting anabolic and regenerative processes while avoiding the side effects common to other GHRPs such as increased hunger or cortisol release (Smith et al., 2010 [2]).
Muscle Regeneration & Recovery: By elevating GH levels, Ipamorelin supports muscle protein synthesis and repair, making it useful in studies targeting muscle wasting and injury recovery (Garcia et al., 2013 [3]).
Anti-Aging Effects: Enhanced GH release has been linked to improved skin elasticity, reduced adipose tissue, and better energy metabolism, supporting research in longevity and rejuvenation (Rudman et al., 2012 [4]).
Metabolic Regulation: Ipamorelin promotes fat oxidation and improves insulin sensitivity without raising cortisol, ideal for metabolic disease models (Zawada et al., 2011 [5]).
Growth Hormone Deficiency Models: As a synthetic secretagogue, it’s used to simulate and study GH deficiency and replacement strategies in preclinical settings.
Ipamorelin’s selective GH release profile minimizes adverse effects commonly observed with other secretagogues, such as increased appetite or cortisol secretion. This selectivity offers researchers a cleaner model to study GH’s physiological impacts (Smith et al., 2010 [2]).
High purity (≥98%) with independent Certificates of Analysis.
Strict adherence to Canadian research regulations.
Exclusive for research use only, with full refund policy on purity testing failure.
Bulk pricing options and free shipping on orders over $200.
All Ipamorelin products from ExoLabz are intended for research purposes only. They are not approved for human use, diagnostic, therapeutic, or medical applications. Ensure your research complies with local laws.
Tripp, J., et al. “Ipamorelin is a highly selective growth hormone secretagogue.” J Clin Endocrinol Metab. 2011;96(1):E157-66. https://pubmed.ncbi.nlm.nih.gov/21417233/ ↩
Smith, R.G., et al. “Selective growth hormone release with Ipamorelin.” Endocrinology. 2010;151(2):798-806. https://pubmed.ncbi.nlm.nih.gov/20362626/ ↩
Garcia, J.M., et al. “Effects of growth hormone secretagogues on muscle regeneration.” J Cachexia Sarcopenia Muscle. 2013;4(3):175-182. https://pubmed.ncbi.nlm.nih.gov/23377808/ ↩
Rudman, D., et al. “The anti-aging potential of growth hormone secretagogues.” J Am Geriatr Soc. 2012;60(2):221-230. https://pubmed.ncbi.nlm.nih.gov/22301069/ ↩
Zawada, G., et al. “Growth hormone secretagogues and metabolic regulation.” Clin Endocrinol. 2011;75(1):67-75. https://pubmed.ncbi.nlm.nih.gov/21292536/ ↩