Ki, IC50 and EC50: What Binding and Potency Figures Actually Measure
Three numbers appear throughout the peptide literature and are routinely treated as interchangeable. They measure different things under different conditions.
Background reading on peptide classes, nomenclature and receptor pharmacology as described in the published literature.
Three numbers appear throughout the peptide literature and are routinely treated as interchangeable. They measure different things under different conditions.
4 min readKLOW is a supplied combination of four separate research peptides rather than a single molecule.
6 min readCJC-1295 is sold and studied in two forms that are frequently conflated. The difference is a single chemical addition…
5 min readThe melanocortin system is a useful case study in receptor selectivity, because a single endogenous ligand family acts across five receptor subtypes with different tissue…
9 min readSS-31, also known as elamipretide, is unusual among research peptides because its mechanism is defined by where it goes rather than by a receptor it binds.
7 min readKisspeptin-10 is the shortest fragment of the KISS1 gene product that retains full receptor activity, which makes it a common tool compound in work on the KISS1R pathway.
5 min readGHK-Cu is frequently described as a tripeptide, which understates what is actually being studied.
8 min readDSIP is a case where the name of a compound has outlasted the confidence of the finding that produced it. Using it well as a research material means understanding that history.
7 min readEpitalon — also transliterated epithalon or epithalone — is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly.
5 min readSelank and Semax are frequently grouped together because they share a development lineage and a common design strategy, not because they act on the same target.
7 min readBPC-157 is among the most widely discussed research peptides and among the most frequently misread.
6 min readTB-500 and thymosin β4 are routinely used as if they were interchangeable names for one substance.
7 min readThe products offered by ExoLabz are intended solely for research purposes. These products are not for human consumption, are not intended for medical use, and have not been approved by the FDA or Health Canada for any therapeutic or diagnostic purpose. ExoLabz makes no claims regarding the safety, efficacy, or intended use of these products outside of a controlled research environment. By purchasing our products, you agree to use them strictly for scientific research and in compliance with all local laws and regulations.

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