Background reading on peptide classes, nomenclature and receptor pharmacology as described in the published literature.
AOD-9604 is the hGH 177-191 fragment with an added N-terminal tyrosine. Here is why the 176-191 label is ambiguous, and what the disulfide bond means for analysis.
Tesamorelin belongs to the same family as CJC-1295 and sermorelin — all are engineered forms of growth hormone-releasing hormone — but it takes a different approach…
Ipamorelin is usually introduced as "a selective secretagogue", which is accurate but uninformative unless you know what it is selective against.
Cyclisation is one of the most consequential modifications available to a peptide chemist.
MOTS-c and SS-31 are both described as mitochondrial peptides, which obscures the fact that they do entirely different things.
Compounds grouped together as "growth hormone peptides" act through two different receptors.
Research peptide names look arbitrary until you know the conventions. Almost every element of a name — brackets, number ranges, suffixes…
GLP-1, GIP and glucagon receptors are class B1 G-protein-coupled receptors. They share architecture, they share a primary signalling route, and they are the targets behind mono-…
Retatrutide (development code LY3437943) is an investigational peptide from Eli Lilly and Company that activates three receptors at once…
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