Description
MOTS-c 20mg – Research-Grade Mitochondrial-Derived Peptide
MOTS-c 20mg is a high-purity, research-grade mitochondrial-derived peptide supplied for laboratory research and analytical use. MOTS-c is a 16-amino-acid peptide encoded within mitochondrial DNA and is referenced in scientific literature for studies of mitochondrial-to-nuclear communication, cellular signaling pathways, and biochemical energy regulation.
This product is strictly intended for laboratory research purposes and is not approved for human consumption, veterinary use, therapeutic application, or clinical procedures.
What Is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a mitochondrial-encoded peptide studied in laboratory models for its involvement in intracellular signaling and mitochondrial function.
In scientific research contexts, MOTS-c has been referenced in relation to:
• Mitochondrial signaling pathways
• AMPK-related biochemical processes
• Glucose and receptor pathway analysis
• Mitonuclear communication and cellular adaptation mechanisms
These applications are limited to controlled laboratory and analytical studies.
Research Applications of MOTS-c 20mg
MOTS-c 20mg is commonly included in laboratory investigations focused on mitochondrial and receptor signalling pathways, including:
• Mitochondrial Function Studies – Biochemical investigations of mitochondria and related pathways
• AMPK Pathway Analysis – Laboratory studies of energy-related signaling mechanisms
• Receptor signalling & Cellular Signaling Models – Analytical studies of intracellular communication and stress response pathways
• Mitonuclear Interaction Research – Experimental exploration of mitochondrial-nuclear signaling
• Laboratory Reference for Biochemical Pathway Analysis – Used as a control or comparative compound in in vitro and ex vivo models
All uses are strictly research-focused and do not indicate or imply human, veterinary, or clinical outcomes.
Product Specifications
• Compound: MOTS-c (Mitochondrial Open Reading Frame of 12S rRNA Type-c)
• Quantity: 20mg
• Grade: Research-Grade Peptide
• Intended Use: Laboratory research and analytical testing only
• Storage: Follow standard laboratory peptide storage and handling protocols
The 20mg format provides a high-capacity supply suitable for multi-phase laboratory protocols or extended experimental studies.
Purity & Quality Assurance
ExoLabz peptides are manufactured under strict quality control standards to ensure consistency, purity, and reliability for laboratory research. ExoLabz products are independently verified for identity and purity. Results are published on this site.
Researchers may submit the peptide for independent third-party testing. If verified testing identifies discrepancies, ExoLabz provides a full refund and testing reimbursement, supporting transparency and research integrity.
Important Research Disclaimer
For Research Purposes Only
MOTS-c 20mg is intended strictly for laboratory research, analytical study, and educational investigation. It is not for human or veterinary consumption, medical use, or therapeutic application. This product has not been approved by Health Canada, FDA, or any regulatory authority.
By purchasing this product, the buyer confirms it will be used exclusively for lawful laboratory research purposes.
Compound identity and specification
Identity data for MOTS-c, published so the material can be checked against an independent record rather than taken on trust. The formula, mass and registry number below are verified against PubChem and can be looked up directly.
| Compound | MOTS-c |
|---|---|
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular formula | C101H152N28O22S2 |
| Molecular mass | 2174.6 g/mol |
| CAS registry number | 1627580-64-6 |
| PubChem | CID 146675088 |
| Vial content | 20 mg |
| Physical form | Lyophilised powder in a sealed vial |
| Analysis | Third-party HPLC; the result for this product is published on this page |
| Supplied for | Laboratory research use only |
Analytical note — MOTS-c. Two methionines, which means two oxidation sites: a single sulfoxide adds 16 Da and a double adds 32, and both appear as earlier-eluting peaks. On a 16-residue peptide these are resolvable, so a certificate that does not mention oxidation state has not told you whether they are present.
Identity references The molecular formula, molecular mass and CAS registry number above are taken from the PubChem record linked in the table, not from a supplier datasheet, so every figure can be checked against an independent source in one click. Sequences are given as reported in the peptide literature, in the one-letter or three-letter convention as appropriate, with any non-standard residue named in full. Where a compound exists in more than one form — a free peptide and a metal complex, a fragment and its parent protein, a modified and an unmodified analog — the form supplied is the one identified here, and the mass on the certificate of analysis is what distinguishes it.
Research Literature
Peer-reviewed studies involving this compound and its class. All findings listed are from in vitro, cell culture or animal models and are provided for scientific reference only. This product is supplied for laboratory research and is not approved for human consumption, clinical, or veterinary use.
- Lee C, et al. Cell Metab. 2015;21(3):443-454. In mouse skeletal muscle and cultured cells, measured inhibition of the folate-methionine cycle and de novo purine biosynthesis with consequent AMPK activation. Source · PMID 25738459
- Kim KH, et al. Cell Metab. 2018;28(3):516-524. In cultured human cells under receptor-signalling stress, measured AMPK-dependent nuclear translocation and occupancy at antioxidant-response-element genes. Source · PMID 29983246
- Reynolds JC, et al. Nat Commun. 2021;12:470. In young, middle-aged and old CD-1 and C57BL/6 mice, measured running capacity, grip strength, gait and skeletal-muscle transcriptomic profiles. Source · PMID 33473109
Related Research Compounds
Browse more compounds in Mitochondrial & Cellular Compounds, or view the full research peptide catalogue.
